acantholysis

[ăk′ăn-thŏlĭ-sĭs, ăk′ən-]
n. pl. ac•an•thol•y•ses (-sēz′)
  1. Separation of individual prickle cells from their neighbors, as in keratosis follicularis.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.