active site

American  

noun

Biochemistry.

1. the part of an enzyme that interacts with the substrate during catalysis.

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active site Scientific  

1. The part of an enzyme where the catalytic activity on the substrate takes place.

2. See more at enzyme

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active site Cultural  

1. The part of an enzyme or antibody where a chemical reaction occurs.

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Etymology

Origin of active site

First recorded in 1960–65

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Example Sentences

See Examples For:

active site

Scientists have nicknamed it the "Pac-Man enzyme" because its molecular structure features a remarkably wide opening where chemical reactions take place, known as the active site.

From Science Daily ● Oct. 16, 2026

At ORNL,Polo-Garzon and Zhang used a technique called steady-state isotopic transient kinetic analysis to measure catalyst efficiency -- the number of times a single active site converts a reactant into a product.

From Science Daily ● Nov. 26, 2024

Forest Service stipulates that the observatory must remain an active site for research, astronomy or education — or be dismantled down to its last historic bolt.

From Los Angeles Times ● Oct. 3, 2023

The active site is where the “action” happens.

From Textbooks ● Apr. 25, 2013

In some cases of enzyme inhibition, an inhibitor molecule is similar enough to a substrate that it can bind to the active site and simply block the substrate from binding.

From Textbooks ● Apr. 25, 2013

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