achondroplasia

American  

[ey-kon-druh-pley-zhuh, -zhee-uh, -zee-uh] / eɪˌkɒn drəˈpleɪ ʒə, -ʒi ə, -zi ə /

noun

Pathology.

1. defective conversion of cartilage into bone, especially at the epiphyses of long bones, producing a type of dwarfism.

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achondroplasia British  

/ eɪˌkɒndrəʊˈpleɪzɪə, eɪˌkɒndrəʊˈplæstɪk /

noun

1. a skeletal disorder, characterized by failure of normal conversion of cartilage into bone, that begins during fetal life and results in dwarfism

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Other Word Forms

• achondroplastic
  adjective

Etymology

Origin of achondroplasia

First recorded in 1890–95; a- ⁶ + chondro- + -plasia

Example Sentences

The reboot was criticised by Game of Thrones actor Peter Dinklage, who has a form of dwarfism called achondroplasia, for being "backward".

From BBC • Mar. 16, 2025

Children with achondroplasia are 50 times more likely to die before the age of five than their peers.

From Science Daily • Nov. 18, 2024

A promising daily tablet is effective at increasing height and improving proportional limb growth in children with achondroplasia, the most common form of dwarfism, according to a new study.

From Science Daily • Nov. 18, 2024

A brass band, clowns, children, wives, babies, the company’s leader and seven performers with achondroplasia, a bone growth disorder that causes the more common type of dwarfism, spilled out into the sun.

From New York Times • Jul. 12, 2023

In certain diseases, such as rickets and inherited syphilis, and in developmental anomalies such as achondroplasia, dwarfing of the skeleton results from defective growth of bone at the ossifying junctions.

From Manual of Surgery Volume First: General Surgery. Sixth Edition. by Thomson, Alexis