active site

American  

noun

Biochemistry.

1. the part of an enzyme that interacts with the substrate during catalysis.

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active site Scientific  

1. The part of an enzyme where the catalytic activity on the substrate takes place.

2. See more at enzyme

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active site Cultural  

1. The part of an enzyme or antibody where a chemical reaction occurs.

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Etymology

Origin of active site

First recorded in 1960–65

Example Sentences

See Examples For:

active site

The model allowed them to identify a protein that interacts with the DNA as it is being transcribed and guides it to the enzyme's active site.

From Science Daily ● Mar. 4, 2024

The drugs work by attaching to a pocket adjacent to the active site, inducing an allosteric conformational change in the protein that prevents it from being activated.

From Science Daily ● Dec. 18, 2023

Forest Service stipulates that the observatory must remain an active site for research, astronomy or education — or be dismantled down to its last historic bolt.

From Los Angeles Times ● Oct. 3, 2023

The chemical properties that emerge from the particular arrangement of amino acid R groups within an active site create the perfect environment for an enzyme’s specific substrates to react.

From Textbooks ● Apr. 25, 2013

The active site is where the “action” happens.

From Textbooks ● Apr. 25, 2013