active site

noun

, Biochemistry.

1. the part of an enzyme that interacts with the substrate during catalysis.

active site

1. The part of an enzyme where the catalytic activity on the substrate takes place.
2. See more at enzyme

active site

1. The part of an enzyme or antibody where a chemical reaction occurs.

Word History and Origins

Origin of active site¹

First recorded in 1960–65

Example Sentences

Second, it must correct the protein’s rogue behavior—for example, shut off the protein’s active site and disable its ability to cause harm.

From Nautilus

The redesign involved swapping out some amino acids at the active site for others.

From Science News For Students