adenylate cyclase

[uh-den-l-it, -eyt, ad-n-l-]

noun

Biochemistry.

1. an enzyme that catalyzes the conversion of ATP to cyclic AMP.

Word History and Origins

Origin of adenylate cyclase¹

First recorded in 1965–70; aden(ine) + -yl + -ate ²

Example Sentences

Manejwala, F., Kaji, E. & Schultz, R. M. Development of activatable adenylate cyclase in the preimplantation mouse embryo and a role for cyclic AMP in blastocoel formation.

Read more on Nature

Through rational drug design and chemical screening, we have identified a lead candidate AC1 inhibitor, NB001, which is relatively selective for AC1 over other adenylate cyclase isoforms.

Read more on Science Magazine