ALS

¹ American

abbreviation

Pathology.

amyotrophic lateral sclerosis.

a.l.s. ² American

abbreviation

autograph letter, signed.

ALS British

abbreviation

autograph letter signed

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Breanna also wants to leave her mark on the world, telling the BBC she wants to be able to help others with ALS and give them "hope".

From BBC • Apr. 10, 2026

Dane died earlier this year of complications from ALS.

From The Wall Street Journal • Apr. 9, 2026

McMichael died April 23, 2025, after a five-year battle with ALS, also known as Lou Gehrig’s disease.

From Los Angeles Times • Apr. 7, 2026

Rui Cardoso, a portfolio manager at Beutel Goodman, recommends Japan’s Shionogi, a pharmaceutical company that is developing drugs for depression and ALS, more commonly known as Lou Gehrig’s disease.

From Barron's • Mar. 19, 2026

There were other people who suffered from ALS, Morrie knew, some of them famous, such as Stephen Hawking, the brilliant physicist and author of A Brief History of Time.

From "Tuesdays with Morrie" by Mitch Albom

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023