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amaurosis

American  
[am-aw-roh-sis] / ˌæm ɔˈroʊ sɪs /

noun

  1. partial or total loss of sight, especially in the absence of a gross lesion or injury.


amaurosis British  
/ ˌæmɔːˈrəʊsɪs, ˌæmɔːˈrɒtɪk /

noun

  1. pathol blindness, esp when occurring without observable damage to the eye

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

Etymology

Origin of amaurosis

1650–60; < Greek: darkening, hindrance to sight, equivalent to amaur ( ós ) dim, dark + -ōsis -osis

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The findings deepen understanding of how mutations in the RPE65 enzyme cause retinal diseases, especially Leber congenital amaurosis, a devastating childhood blinding disease.

From Science Daily • Feb. 22, 2024

Toben has a rare genetic condition called Leber's congenital amaurosis.

From BBC • May 27, 2022

Trial participants have Leber congenital amaurosis type 10, caused by a mutated gene that the trial aimed to fix.

From Science Magazine • Oct. 6, 2021

Last July, the pharmaceutical companies Editas Medicine in Cambridge, Massachusetts, and Allergan in Dublin launched a trial to treat the genetic disorder Leber congenital amaurosis 10, which can cause blindness, by editing eye cells.

From Nature • Jan. 5, 2020

In amaurosis the pupil is dilated to its full extent; the eye looks clear, but does not respond to light.

From Special Report on Diseases of the Horse by Michener, Charles B.

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