- a test that exposes a strain of bacteria to a chemical compound in order to determine the mutagenic potential of the compound.
Origin of Ames test
1975–80; after U.S. biochemist Bruce N. Ames (born 1928), who developed the test
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018
- a method of preliminary screening for carcinogens, based on their ability to cause mutations in bacteria
named after Bruce Ames (born 1928), US biochemist who invented the test
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012
- A test in which strains of Salmonella that are unable to synthesize histidine are introduced into a test substance lacking in histidine. If the strains then regain the ability to synthesize histidine, the substance is considered mutagenic and thus carcinogenic.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.