amuck

If you give steroids to a patient who is not yet exhibiting signs of an overactive immune system, you may actually make them sicker by allowing SARS-CoV-2 to run amuck.

I learned to swing an axe by cutting down saplings, and ran "amuck" among them just as my elders did among the larger trees.

The elephant was not running amuck, though he might eventually work himself into that blind ungovernable rage.

As a wild beast is tied to keep it from running amuck, so the Law bridles mad and furious man to keep him from running wild.