pyrimidine

American  

[pahy-rim-i-deen, pi-, pir-uh-mi-deen, -din] / paɪˈrɪm ɪˌdin, pɪ-, ˈpɪr ə mɪˌdin, -dɪn /

noun

Biochemistry.

1. a heterocyclic compound, C 4 H 4 N 2 , that is the basis of several important biochemical substances.

2. one of several pyrimidine derivatives, especially the bases cytosine, thymine, and uracil, which are fundamental constituents of nucleic acids.

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pyrimidine British  

/ paɪˈrɪmɪˌdiːn /

noun

1. a liquid or crystalline organic compound with a penetrating odour; 1,3-diazine. It is a weakly basic soluble heterocyclic compound and can be prepared from barbituric acid. Formula: C 4 H 4 N 2

2. Also called: pyrimidine base. any of a number of similar compounds having a basic structure that is derived from pyrimidine, including cytosine, thymine, and uracil, which are constituents of nucleic acids

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pyrimidine Scientific  

/ pī-rĭm′ĭ-dēn′ /

1. Any of a group of organic compounds having a single six-member ring in which the first and third atoms are nitrogen and the rest are carbon. Pyrimidines include the bases cytosine, thymine, and uracil, which are components of DNA and RNA. Pyrimidine rings are also components of several larger compounds, such as thiamine and some synthetic barbiturates.

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Etymology

Origin of pyrimidine

1880–85; blend of pyridine and imide

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Example Sentences

See Examples For:

pyrimidine

Researchers say cancer cells need to run out of pyrimidine building blocks, including uridine nucleotides, before the cells will self-destruct.

From Science Daily ● Nov. 26, 2024

Cancer cells must have access to pyrimidine supplies to produce more cancer cells and to produce uridine nucleotides, a primary fuel source for cancer cells as they rapidly reproduce, grow, and die.

From Science Daily ● Nov. 26, 2024

Damage to DNA induced by ultraviolet radiation occurs with the formation of bonds between an adjacent pair of pyrimidine nucleotides, thymine and cytosine, on the same strand of DNA.

From Textbooks ● Jun. 9, 2022

Base pairing takes place between a purine and pyrimidine; namely, A pairs with T and G pairs with C. Adenine and thymine are complementary base pairs, and cytosine and guanine are also complementary base pairs.

From Textbooks ● Jun. 9, 2022

This could only mean that the 3.4 A-thick purine and pyrimidine bases were stacked on top of each other in a direction perpendicular to the helical axis.

From "Double Helix" by James D. Watson

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