auranofin

[aw-ran-uh-fin]

noun

Pharmacology.

1. a gold-containing compound, C 20 H 34 AuO 9 PS, used orally in the treatment of rheumatoid arthritis.

Word History and Origins

Origin of auranofin¹

Coinage apparently based on aurum; following syllables unexplained

Example Sentences

Today, gold-based cancer treatments are gaining global traction, with advancements such as the repurposing of the anti-arthritic drug auranofin, now showing promise in clinical trials for oncology.

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Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis.

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Because auranofin has already been approved for use in humans, we can save years of expensive development.

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"Although auranofin has to date only been tested in animal models of amoebic disease, this means that there is now a potential alternative treatment for individual cases where metronidazole fails to cure the infection or in the event resistance to metronidazole emerge as a clinical problem in the future."

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It showed that auranofin was much better than the current treatment, metronidazole, at killing Entamoeba histolytica.

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