caffeine

American  

[ka-feen, kaf-een, kaf-ee-in] / kæˈfin, ˈkæf in, ˈkæf i ɪn /

Rarely caffein

noun

1. Chemistry, Pharmacology. a white, crystalline, bitter alkaloid, C 8 H 10 N 4 O 2 , usually derived from coffee or tea: used in medicine chiefly as a nervous system stimulant.

2. Informal. a drink, usually coffee or tea, containing this stimulant.

   We sipped our caffeine on the balcony with its views of sea stacks, rocky coves, and the ever-changing ocean.

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caffeine British  

/ ˈkæfiːn, ˈkæfɪˌiːn /

noun

1. a white crystalline bitter alkaloid responsible for the stimulant action of tea, coffee, and cocoa: a constituent of many tonics and analgesics. Formula: C 8 H 10 N 4 O 2 See also xanthine

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caffeine Scientific  

/ kă-fēn′ /

1. A bitter white alkaloid found in tea leaves, coffee beans, and various other plant parts. It is a mild stimulant. Caffeine is a xanthine and similar in structure to theobromine and theophylline. Chemical formula: C ₈ H ₁₀ N ₄ O ₂ .

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Other Word Forms

• caffeinic
  adjective
• noncaffeine
  noun
• noncaffeinic
  adjective

Etymology

Origin of caffeine

First recorded in 1820–30; from French caféine, equivalent to café coffee + -ine -ine ²

Compare meaning

How does caffeine compare to similar and commonly confused words? Explore the most common comparisons:

• theobromine vs. caffeine

Explanation

Good morning! Caffeine keeps you awake! It’s that zippy chemical found in coffee, tea, and sodas. In fact, it comes from the German word for “coffee.” Caffeine is a chemical found naturally in the seeds of some fruits and nuts, like coffee beans and kola nuts. It’s a stimulant, so it makes people feel alert. People love to start their mornings with coffee to help them perk up for the day. The word comes from the German Kaffein, coined in 1830 by a chemist who combined the word for "coffee," Kaffee, with -in, a German chemical suffix.

Example Sentences

As a vehicle for jitters, Diet Coke also contains significantly more caffeine than both regular Coca-Cola and Coke Zero.

From The Wall Street Journal • May 20, 2026

Regular coffee drinkers also tend to clear caffeine from the body more efficiently.

From Science Daily • May 18, 2026

Anyone with these conditions should discuss caffeine intake with their doctor.

From Science Daily • May 18, 2026

Coffee and tea contain other compounds beyond caffeine that may benefit the brain as well.

From Science Daily • May 13, 2026

The doctors had told him to lay off the caffeine, but he figured they’d make an exception for today.

From "Eleven" by Tom Rogers

Related Words

• cappuccino
• espresso