caffeine

American  

[ka-feen, kaf-een, kaf-ee-in] / kæˈfin, ˈkæf in, ˈkæf i ɪn /

Rarely caffein

noun

1. Chemistry, Pharmacology. a white, crystalline, bitter alkaloid, C 8 H 10 N 4 O 2 , usually derived from coffee or tea: used in medicine chiefly as a nervous system stimulant.

2. Informal. a drink, usually coffee or tea, containing this stimulant.

   We sipped our caffeine on the balcony with its views of sea stacks, rocky coves, and the ever-changing ocean.

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caffeine British  

/ ˈkæfiːn, ˈkæfɪˌiːn /

noun

1. a white crystalline bitter alkaloid responsible for the stimulant action of tea, coffee, and cocoa: a constituent of many tonics and analgesics. Formula: C 8 H 10 N 4 O 2 See also xanthine

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caffeine Scientific  

/ kă-fēn′ /

1. A bitter white alkaloid found in tea leaves, coffee beans, and various other plant parts. It is a mild stimulant. Caffeine is a xanthine and similar in structure to theobromine and theophylline. Chemical formula: C ₈ H ₁₀ N ₄ O ₂ .

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Other Word Forms

• caffeinic adjective
• noncaffeine noun
• noncaffeinic adjective

Etymology

Origin of caffeine

First recorded in 1820–30; from French caféine, equivalent to café coffee + -ine -ine ²

Compare meaning

How does caffeine compare to similar and commonly confused words? Explore the most common comparisons:

• theobromine vs. caffeine

Explanation

Good morning! Caffeine keeps you awake! It’s that zippy chemical found in coffee, tea, and sodas. In fact, it comes from the German word for “coffee.” Caffeine is a chemical found naturally in the seeds of some fruits and nuts, like coffee beans and kola nuts. It’s a stimulant, so it makes people feel alert. People love to start their mornings with coffee to help them perk up for the day. The word comes from the German Kaffein, coined in 1830 by a chemist who combined the word for "coffee," Kaffee, with -in, a German chemical suffix.

Example Sentences

Kirkland Signature energy drinks mimic Celsius’s look, flavors, and 200 milligrams of caffeine, causing Celsius shares to fall.

From The Wall Street Journal • Mar. 25, 2026

Both brands’ 12-ounce cans carry the same 200 milligrams of caffeine, too.

From The Wall Street Journal • Mar. 25, 2026

Even so, nectar contains other compounds, such as nicotine and caffeine, that are known to influence animal behavior.

From Science Daily • Mar. 25, 2026

Higher levels of caffeine intake did not appear to cause harm.

From Science Daily • Mar. 18, 2026

Just a whole bunch of anonymous New Yorkers lining up for their jolt of caffeine.

From "What If It's Us" by Becky Albertalli and Adam Silvera

Related Words

• cappuccino
• espresso