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calcitriol

American  
[kal-si-tree-awl, -ol] / kælˈsɪ triˌɔl, -ˌɒl /

noun

  1. Biochemistry. a vitamin D compound, C 27 H 44 O 3 , occurring in humans as a hormone derived from cholesterol, that acts in the regulation and absorption of calcium.

  2. Pharmacology. a preparation of this compound, used in the treatment of osteoporosis and bone fracture.


Etymology

Origin of calcitriol

1975–80; apparently calci(um) + triol

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Example Sentences

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PTH triggers the formation of calcitriol, an active form of vitamin D, which acts on the intestines to increase absorption of dietary calcium.

From Textbooks • Jun. 9, 2022

It triggers the kidneys to inhibit the formation of calcitriol from vitamin D3 and to increase phosphorus excretion.

From Textbooks • Jun. 19, 2013

Calcium and phosphate are regulated by PTH, calcitriol, and calcitonin.

From Textbooks • Jun. 19, 2013

Among other things, calcitriol shuts off the mechanisms that break down fat and activates those that make it.

From Time Magazine Archive

In the absence of calcium, levels of the hormone calcitriol increase.

From Time Magazine Archive