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calcitriol

American  
[kal-si-tree-awl, -ol] / kælˈsɪ triˌɔl, -ˌɒl /

noun

  1. Biochemistry. a vitamin D compound, C 27 H 44 O 3 , occurring in humans as a hormone derived from cholesterol, that acts in the regulation and absorption of calcium.

  2. Pharmacology. a preparation of this compound, used in the treatment of osteoporosis and bone fracture.


Etymology

Origin of calcitriol

1975–80; apparently calci(um) + triol

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Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

In the liver, cholecalciferol is converted to an intermediate that travels to the kidneys and is further converted to calcitriol, the active form of vitamin D3.

From Textbooks • Jun. 19, 2013

Additionally, calcitriol, the active form of vitamin D, is produced by the kidneys and stimulates the absorption of calcium and phosphate from the digestive tract.

From Textbooks • Jun. 19, 2013

It triggers the kidneys to inhibit the formation of calcitriol from vitamin D3 and to increase phosphorus excretion.

From Textbooks • Jun. 19, 2013

In the absence of calcium, levels of the hormone calcitriol increase.

From Time Magazine Archive

Among other things, calcitriol shuts off the mechanisms that break down fat and activates those that make it.

From Time Magazine Archive