calmodulin

American  

[kal-moj-uh-lin] / kælˈmɒdʒ ə lɪn /

noun

Biochemistry.

1. a calcium-binding protein occurring in many tissues and participating in the regulation of many biochemical and physiological processes.

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calmodulin British  

/ kəlˈmɒdjʊlɪn /

noun

1. biochem a protein found in most living cells; it regulates many enzymic processes that are dependent on calcium

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Etymology

Origin of calmodulin

First recorded in 1975–80; cal(cium) + modul(ate) + -in ²

Example Sentences

When the two examined the sequence, they found a mutation in a gene, CALM2, encoding a protein called calmodulin whose misfunction had already been implicated in heart arrythmias and disorders and even deaths in infancy.

From Science Magazine • Jun. 6, 2023

In a smooth muscle fiber, external Ca++ ions passing through opened calcium channels in the sarcolemma, and additional Ca++ released from SR, bind to calmodulin.

From Textbooks • Jun. 19, 2013

The calcium ions then act as second messengers in two ways: they can influence enzymatic and other cellular activities directly, or they can bind to calcium-binding proteins, the most common of which is calmodulin.

From Textbooks • Jun. 19, 2013

The influx of extracellular Ca++ ions, which diffuse into the sarcoplasm to reach the calmodulin, accounts for most of the Ca++ that triggers contraction of a smooth muscle cell.

From Textbooks • Jun. 19, 2013

Upon binding calcium, calmodulin is able to modulate protein kinase within the cell.

From Textbooks • Jun. 19, 2013