CD4

American  

noun

1. a protein on the surface of T cells and other cells, functioning as a receptor for the AIDS virus antigen.

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Etymology

Origin of CD4

1980–85; c(luster of) d(ifferentiation) 4

Example Sentences

ART works so powerfully that it virtually shuts down the ability of these integrated viral genes to make new HIVs, but some of the infected CD4 cells remain in various tissues—the reservoirs.

From Science Magazine • Mar. 7, 2024

Postdoctoral researcher and study co-author Ashley Bennett offers a play-by-play: As the virus feels for its best attachment point on a human T-cell, the host cell's CD4 receptor is the first thing it latches onto.

From Science Daily • Feb. 2, 2024

Together, the new findings underscore the importance of specific studies on the immune response among people with HIV, especially those with lower CD4 white blood cells.

From Science Daily • Jan. 12, 2024

They analyzed the amount of H.I.V. and the number of CD4 cells, a type of immune system cell, in these patients.

From New York Times • Feb. 21, 2023

In the cases where people had few CD4 cells, mpox’s normally small skin lesions grew into large necrotizing patches and their infection sometimes spread to the lungs or caused severe secondary infections with bacteria.

From Science Magazine • Feb. 20, 2023