Chédiak-Steinbrinck-Higashi syndrome

[ shādyäk-stīnbrĭngk-hĭ-gä'shē, -shtīn- ]


An inherited syndrome marked by abnormalities of granulation and nuclear structure of all types of white blood cells; it is often accompanied by hepatosplenomegaly, lymphadenopathy, anemia, thrombocytopenia, radiologic changes of bones, lungs, and heart, skin and psychomotor abnormalities, and susceptibility to infection.Chédiak-Higashi disease Chédiak-Steinbrinck-Higashi anomaly
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.