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choline

American  
[koh-leen, kol-een] / ˈkoʊ lin, ˈkɒl in /

noun

  1. Biochemistry. a quaternary ammonium cation, C 5 H 14 N + O, one of the B-complex vitamins, found in the lecithin of many plants and animals.

  2. choline hydroxide, C 5 H 15 NO 2 , the viscous, strongly alkaline commercial form of this compound, usually synthesized, used as a feed supplement, especially for poultry, and in medicine in certain liver conditions.

  3. choline chloride, C 5 H 14 ClNO.


choline British  
/ ˈkəʊliːn, -ɪn, ˈkɒl- /

noun

  1. a colourless viscous soluble alkaline substance present in animal tissues, esp as a constituent of lecithin: used as a supplement to the diet of poultry and in medicine for preventing the accumulation of fat in the liver. Formula:[(CH 3 ) 3 NCH 2 CH 2 OH] + OH

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

choline Scientific  
/ kōlēn′ /
  1. A natural amine often classed in the vitamin B complex. It is incorporated into the structure of many other biologically important molecules, such as acetylcholine and lecithin. Chemical formula: C 5 H 15 NO 2 .


Etymology

Origin of choline

First recorded in 1855–60; chol- + -ine 2

Example Sentences

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See Examples For:

Even more striking, feeding the worms phosphatidylcholine or its precursor, choline, restored a more youthful mitochondrial structure within just two days.

From Science Daily Jun. 11, 2026

Controlled trials would be needed to test whether changing choline intake can alter brain chemistry or improve anxiety outcomes.

From Science Daily May 16, 2026

Norepinephrine is often elevated in anxiety disorders, and the UC Davis researchers suggest that this heightened arousal may increase the brain's demand for choline.

From Science Daily May 16, 2026

People with anxiety disorders may share a measurable change in brain chemistry involving choline, an essential nutrient tied to memory, mood, cell structure, and nerve signaling.

From Science Daily May 16, 2026

In another group of extracts from brain or nerve tissue, amino-ethanol H2NCH2CH2OH is found instead of the choline of lecithin.

From History of Phosphorus by Farber, Eduard

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