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classical pathway

American  

noun

Immunology.
  1. the activation of complement by an antigen-antibody reaction.


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Figure 21.13 Complement Cascade and Function The classical pathway, used during adaptive immune responses, occurs when C1 reacts with antibodies that have bound an antigen.

From Textbooks Jun. 19, 2013

The classical pathway is similar, except the early stages of activation require the presence of antibody bound to antigen, and thus is dependent on the adaptive immune response.

From Textbooks Jun. 19, 2013

Additionally, complement functions in the adaptive immune response as well, in what is called the classical pathway.

From Textbooks Jun. 19, 2013

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