clofibrate

American  

[kloh-fahy-breyt, -fib-reyt] / kloʊˈfaɪ breɪt, -ˈfɪb reɪt /

noun

Pharmacology.

1. a substance, C 12 H 15 ClO 3 , used principally to reduce elevated plasma triglyceride and cholesterol levels.

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Etymology

Origin of clofibrate

1960–65; clofibr(ic acid) (perhaps c(h)lo(ro)- ² + fibr- + -ic ) + -ate ²

Example Sentences

So the authors put clofibrate into the water of normal male mice, and mice that had the human TAS1R3 gene.

From Scientific American

When these mice were given the drug clofibrate, which inhibits the human receptor, the males became sterile due to malformed and fewer sperm.

From Scientific American

And if you got rid of the clofibrate?

From Scientific American

The drug clofibrate that belongs to a class of chemicals called fibrates, which are frequently prescribed to treat lipid disorders, such as high blood cholesterol or high levels of triglycerides.

From Scientific American

The mice quickly became fertile again once clofibrate was removed from their diet.

From Scientific American