clofibrate

American  

[kloh-fahy-breyt, -fib-reyt] / kloʊˈfaɪ breɪt, -ˈfɪb reɪt /

noun

Pharmacology.

1. a substance, C 12 H 15 ClO 3 , used principally to reduce elevated plasma triglyceride and cholesterol levels.

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Etymology

Origin of clofibrate

1960–65; clofibr(ic acid) (perhaps c(h)lo(ro)- ² + fibr- + -ic ) + -ate ²

Example Sentences

But the male mice with a knockout for GNAT3 and TAS1R3 with the human TAS1R3 blocked by the clofibrate were completely infertile.

From Scientific American • Jul. 1, 2013

And if you got rid of the clofibrate?

From Scientific American • Jul. 1, 2013

These are mice that were knockouts for GNAT3 and mouse TAS1R3 with human TAS1R3, and then treated with clofibrate.

From Scientific American • Jul. 1, 2013

There were twelve fatal heart attacks, but only four among men taking clofibrate.

From Time Magazine Archive

So far, there have been 47 new heart attacks, 37 among the 700 men on the placebo, but only ten among those on clofibrate.

From Time Magazine Archive