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Coffin-Siris syndrome

(kŏfĭn-sĭrĭs)
n.
  1. An inherited syndrome that in males causes mental retardation with a wide bulbous nose and low nasal bridge, moderate hirsutism, and digital anomalies with nail hypoplasia. In females the syndrome may cause digital abnormalities and mild mental retardation.Coffin-Lowry syndrome
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.