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collagen

American  
[kol-uh-juhn] / ˈkɒl ə dʒən /

noun

Biochemistry.
  1. any of a class of extracellular proteins abundant in higher animals, especially in the skin, bone, cartilage, tendon, and teeth, forming strong insoluble fibers and serving as connective tissue between cells, yielding gelatin when denatured by boiling.


collagen British  
/ ˈkɒlədʒən, ˌkɒləˈdʒɛnɪk, kəˈlædʒənəs /

noun

  1. a fibrous scleroprotein of connective tissue and bones that is rich in glycine and proline and yields gelatine on boiling

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

collagen Scientific  
/ kŏlə-jən /
  1. Any of various tough, fibrous proteins found in bone, cartilage, skin, and other connective tissue. Collagens have great tensile strength, and provide these body structures with the ability to withstand forces that stretch them. Collagens consist of three polypeptide chains arranged in a triple helix, and are bundled together in fibers. When boiled in water, collagen is converted into gelatin.


Other Word Forms

  • collagenic adjective
  • collagenous adjective

Etymology

Origin of collagen

First recorded in 1860–65; from Greek kólla “glue” + -gen

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

In test tube studies, bone forming cells quickly moved into the structured hydrogel and began producing collagen, a key building block of bone.

From Science Daily • Mar. 3, 2026

Experts looked at the available evidence and say they are highly confident that collagen pills or powder provide "some legitimate" skin gains if taken over time but are no quick fix.

From BBC • Feb. 26, 2026

From early adulthood onwards, the body produces less collagen and existing collagen breaks down at a slightly faster rate.

From BBC • Feb. 26, 2026

As people age, natural collagen production slows, which contributes to visible and physical changes.

From Science Daily • Jan. 29, 2026

Ebola attacks connective tissue with particular ferocity; it multiplies in collagen, the chief constituent protein of the tissue that holds the organs together.

From "The Hot Zone" by Richard Preston