collagen

American  

[kol-uh-juhn] / ˈkɒl ə dʒən /

noun

Biochemistry.

• collagens
  plural

1. any of a class of extracellular proteins abundant in higher animals, especially in the skin, bone, cartilage, tendon, and teeth, forming strong insoluble fibers and serving as connective tissue between cells, yielding gelatin when denatured by boiling.

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collagen British  

/ ˈkɒlədʒən, ˌkɒləˈdʒɛnɪk, kəˈlædʒənəs /

noun

1. a fibrous scleroprotein of connective tissue and bones that is rich in glycine and proline and yields gelatine on boiling

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collagen Scientific  

/ kŏl′ə-jən /

1. Any of various tough, fibrous proteins found in bone, cartilage, skin, and other connective tissue. Collagens have great tensile strength, and provide these body structures with the ability to withstand forces that stretch them. Collagens consist of three polypeptide chains arranged in a triple helix, and are bundled together in fibers. When boiled in water, collagen is converted into gelatin.

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Other Word Forms

Derived Forms

• collagenic
  adjective
• collagenous
  adjective

Inflected Forms

Nouns

• collagens
  plural

Etymology

Origin of collagen

First recorded in 1860–65; from Greek kólla “glue” + -gen

Explanation

Collagen is a protein that keeps your bones strong and allows your skin to stretch and heal after injuries. One of the reasons we get wrinkles as we age is because we gradually lose collagen. Collagen is the most common protein in all mammals, including humans, and it's an important one, as it helps keep us strong and healthy. The word comes from a Greek root, kolla that means "glue." Most collagen is found in the connective tissue between our bones, and its loss can result in achy joints. Some people believe that taking collagen supplements (made from tissue and bones of animals) can improve their health and reduce this pain.

Example Sentences

See Examples For:

collagen collagens

"From a research perspective this is a major milestone. It positions keratin as a potential new class of regenerative biomaterial that could challenge the long-standing reliance on collagen," said Dr. Sherif Elsharkawy.

From Science Daily ● Aug. 12, 2026

"Our hormones affect our skin, they affect our collagen, so a lot of people find their skin becomes drier, their complexion not so bright, they might have acne and spots," Newson explains.

From BBC ● Aug. 3, 2026

Other popular treatments include fractional laser resurfacing, which is meant to stimulate collagen production, as well as surgical procedures that remove fat from other parts of the body to inject into the face.

From The Wall Street Journal ● Jul. 28, 2026

An international research team led by Hiroshima University has developed a technique that can reveal extremely early changes in human skin collagen, long before the damage becomes visible under conventional imaging.

From Science Daily ● Jul. 20, 2026

Ebola attacks connective tissue with particular ferocity; it multiplies in collagen, the chief constituent protein of the tissue that holds the organs together.

From "The Hot Zone" by Richard Preston

Scarring occurs from the secretion and accumulation of various components -- primarily proteins known as collagens -- into the space between individual cells, usually occurring as a response to injury or damage.

From Science Daily ● Apr. 24, 2024

Within the cuticle layer, the research study focused on collagens, which are the most abundant family of proteins in our bodies and help keep bodily materials conjoined.

From Science Daily ● Dec. 21, 2023

Microbes growing in giant fermenters express each of these collagens, which are strained and refined into pure protein.

From New York Times ● Aug. 2, 2022

Still another genetically engineers microbes to produce collagens, which are then turned into textile fibers.

From Scientific American ● Mar. 28, 2022

Not nearly as inactive as the name suggests, senescent cells contribute to chronic inflammation and interfere with protective collagens.

From The New Yorker ● Oct. 28, 2019