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• colony-stimulating factor
  colony-stimulating factor

  noun

  immunol any of a number of substances, secreted by the bone marrow, that cause stem cells to proliferate and differentiate, forming colonies of specific blood cells. Synthetic forms are being tested for their ability to reduce the toxic effects of chemotherapy
• colony stimulating factor
  colony stimulating factor

  Any of various glycoproteins that act to promote the production and differentiation of specific blood cell types. Colony stimulating factors circulate in the blood, acting as hormones, and are also secreted locally. An example is erythropoietin, which is produced in the kidney and regulates the formation of red blood cells from progenitor cells in the bone marrow.

colony-stimulating factor

British  

noun

1.  CSF.  immunol any of a number of substances, secreted by the bone marrow, that cause stem cells to proliferate and differentiate, forming colonies of specific blood cells. Synthetic forms are being tested for their ability to reduce the toxic effects of chemotherapy

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colony stimulating factor Scientific  

1. Any of various glycoproteins that act to promote the production and differentiation of specific blood cell types. Colony stimulating factors circulate in the blood, acting as hormones, and are also secreted locally. An example is erythropoietin, which is produced in the kidney and regulates the formation of red blood cells from progenitor cells in the bone marrow.

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Example Sentences

"Currently, the main treatment for low white blood cell counts is G-CSF, or granulocyte colony-stimulating factor, which is produced by the body and can be administered as a drug," said Jaschke.

From Science Daily • Jan. 31, 2024

Giving mice a drug that blocked the critical protein colony-stimulating factor 1, which microglia need to survive, was shown to remove around 90 percent of microglia in the brain.

From Scientific American • Jul. 26, 2021

GM-CSF, or granulocyte- macrophage colony-stimulating factor, is one of at least five hormones that boost the production of white blood cells in the marrow.

From Time Magazine Archive

Interferons, tumor necrosis factor, interleukin-1 and a substance called colony-stimulating factor all play a role in the normal functioning of the immune system and may ultimately find a place in the treatment of cancer.

From Time Magazine Archive