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congenital ichthyosiform erythroderma

n.
  1. A hereditary skin disease characterized by diffuse chronic erythema and the formation of thickened, scaly skin on the palms and soles, sometimes associated with ocular and neural changes.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.