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connective-tissue disease

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n.
Any of a group of noninheritable diseases that affect the connective tissue, such as rheumatic fever and rheumatoid arthritis, and that are characterized by fever, pain, stiffness, and inflammation.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

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