creatine

American  

[kree-uh-teen, -tin] / ˈkri əˌtin, -tɪn /

noun

Biochemistry.

1. an amino acid, C 4 H 9 N 3 O 2 , that is a constituent of the muscles of vertebrates and is phosphorylated to store energy used for muscular contraction.

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creatine British  

/ ˈkriːətɪn, ˈkriːəˌtiːn, -tɪn /

noun

1. an important metabolite involved in many biochemical reactions and present in many types of living cells

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creatine Scientific  

/ krē′ə-tēn′,-tĭn /

1. A nitrogenous organic acid that is found in the muscle tissue of vertebrates, mainly combined with phosphorus, and that supplies energy for muscle contraction. Chemical formula: C ₄ H ₉ N ₃ O ₂ .

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Etymology

Origin of creatine

First recorded in 1830–40; creat- (from Greek kreat-, stem of kréas “flesh”) + -ine ² ( def. )

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Compare meaning

How does creatine compare to similar and commonly confused words? Explore the most common comparisons:

• creatine vs. creatinine

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Example Sentences

See Examples For:

creatine

That result fits with previous evidence showing that creatine primarily supports muscular strength and power rather than aerobic fitness.

From Science Daily ● Sep. 30, 2026

Among participants who did not join the exercise program, those taking creatine gained roughly 2.4 pounds of lean tissue over the 12 weeks.

From Science Daily ● Sep. 30, 2026

The body makes creatine naturally, and it is also found in foods including meat and fish.

From Science Daily ● Sep. 30, 2026

During the 1992 Barcelona Games, investigative reporter Doug Gillon had learned of a 'secret trial' involving British athletes and seen a box of their Ergomax C150 – effervescent creatine tablets.

From BBC ● Aug. 20, 2026

So notorious is this that it used to be held that the specific poison of glanders was generated in connection with the excess of creatine, creatinine, and lactic acid resulting from muscular action.

From A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases by Various

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