creatine

American  

[kree-uh-teen, -tin] / ˈkri əˌtin, -tɪn /

noun

Biochemistry.

1. an amino acid, C 4 H 9 N 3 O 2 , that is a constituent of the muscles of vertebrates and is phosphorylated to store energy used for muscular contraction.

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creatine British  

/ -tɪn, ˈkriːətɪn, ˈkriːəˌtiːn /

noun

1. an important metabolite involved in many biochemical reactions and present in many types of living cells

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creatine Scientific  

/ krē′ə-tēn′,-tĭn /

1. A nitrogenous organic acid that is found in the muscle tissue of vertebrates, mainly combined with phosphorus, and that supplies energy for muscle contraction. Chemical formula: C ₄ H ₉ N ₃ O ₂ .

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Etymology

Origin of creatine

First recorded in 1830–40; creat- (from Greek kreat-, stem of kréas “flesh”) + -ine ² ( def. )

Compare meaning

How does creatine compare to similar and commonly confused words? Explore the most common comparisons:

• creatine vs. creatinine

Example Sentences

A team led by Lawrence Kazak at McGill University's Rosalind and Morris Goodman Cancer Institute has now identified the molecular trigger for this alternative system, known as the futile creatine cycle.

From Science Daily • May 12, 2026

From helping cells produce energy to its possible role in treating certain health conditions, creatine has become an increasingly important focus of research.

From Science Daily • May 4, 2026

Studies suggest potential benefits for memory, mood and processing speed, particularly in people with naturally lower creatine levels, such as older adults.

From Science Daily • May 4, 2026

Not all consumed creatine is absorbed by the body.

From Science Daily • May 4, 2026

Both creatine and creatinine are readily soluble in water.

From The Chemistry of Food and Nutrition by Duncan, A. W.