creatine

American  

[kree-uh-teen, -tin] / ˈkri əˌtin, -tɪn /

noun

Biochemistry.

1. an amino acid, C 4 H 9 N 3 O 2 , that is a constituent of the muscles of vertebrates and is phosphorylated to store energy used for muscular contraction.

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creatine British  

/ ˈkriːətɪn, ˈkriːəˌtiːn, -tɪn /

noun

1. an important metabolite involved in many biochemical reactions and present in many types of living cells

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creatine Scientific  

/ krē′ə-tēn′,-tĭn /

1. A nitrogenous organic acid that is found in the muscle tissue of vertebrates, mainly combined with phosphorus, and that supplies energy for muscle contraction. Chemical formula: C ₄ H ₉ N ₃ O ₂ .

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Etymology

Origin of creatine

First recorded in 1830–40; creat- (from Greek kreat-, stem of kréas “flesh”) + -ine ² ( def. )

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Compare meaning

How does creatine compare to similar and commonly confused words? Explore the most common comparisons:

• creatine vs. creatinine

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Example Sentences

See Examples For:

creatine

More research is needed to better understand the connection between creatine and cognition; but the supplement may be beneficial for brain health, particularly in older adults and for issues related to sleep deprivation.

From Los Angeles Times ● Oct. 19, 2026

Shopping for creatine: Creatine is available in powder, capsule, liquid and even energy bar form.

From Los Angeles Times ● Oct. 19, 2026

Ansari stresses that, as with any supplement, creatine should be complementary to diet.

From Los Angeles Times ● Oct. 19, 2026

Nouraei says creatine may also aid the uncomfortable symptoms of perimenopause and menopause.

From Los Angeles Times ● Oct. 19, 2026

In vertebrates, the basis for the phosphoric acid is creatine, whereas invertebrates have arginine instead.

From History of Phosphorus by Eduard Farber

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