Creutzfeldt-Jakob disease

American  

[kroits-felt yah-kawp] / ˈkrɔɪts fɛlt ˈjɑ kɔp /

Or Creutzfeldt-Jacob disease

noun

Pathology.

1. a rare, usually fatal brain disorder thought to be caused by an infectious prion and characterized by progressive dementia, blindness, and involuntary movements.

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Creutzfeldt-Jakob disease British  

/ ˈkrɔɪtsfɛlt ˈjɑːkɒp /

noun

1. pathol a fatal slow-developing disease that affects the central nervous system, characterized by mental deterioration and loss of coordination of the limbs. It is thought to be caused by an abnormal prion protein in the brain

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Creutzfeldt-Jakob disease Scientific  

/ kroits′fĕlt-yä′kôp /

1. A rare, usually fatal encephalopathy that occurs most often in middle age and is likely caused by a prion. It is characterized by progressive dementia and gradual loss of muscle control. The disease is named after its discoverers, German pathologist Hans Gerhard Creutzfeldt (1885–1964) and German neurologist Alfons Maria Jakob (1884–1931).

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Etymology

Origin of Creutzfeldt-Jakob disease

1965–70; after German physicians Hans G. Creutzfeldt (1885–1964) and Alfons Jakob (1884–1931)

Example Sentences

See Examples For:

Creutzfeldt-Jakob disease

Misfolding of the prion protein triggers prion diseases such as Creutzfeldt-Jakob disease.

From Science Daily ● Dec. 4, 2023

Anyone can donate their body with the exception of people with Creutzfeldt-Jakob disease, hepatitis B or C, HIV and active tuberculosis.

From Los Angeles Times ● May 19, 2023

The American Red Cross, which provides about 40% of the U.S. supply, last month began accepting donors previously deferred because of the risk of mad cow disease, formally known as variant Creutzfeldt-Jakob disease, or vCJD.

From Seattle Times ● Nov. 20, 2022

They are thought to contribute to several progressive brain disorders, including mad cow disease and Creutzfeldt-Jakob disease.

From Textbooks ● Jun. 9, 2022

When this illness crossed the species barrier from animal to human in 1996, it took the form of variant Creutzfeldt-Jakob disease, or vCJD.

From The Guardian ● Mar. 22, 2018