Crooke's hyaline degeneration

n.

A form of degeneration in which the cytoplasmic granules of basophil cells of the pituitary gland are replaced by hyaline, characteristic of Cushing's syndrome.

The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.