cyclophosphamide

American  

[sahy-kluh-fos-fuh-mahyd, -mid, sik-luh-] / ˌsaɪ kləˈfɒs fəˌmaɪd, -mɪd, ˌsɪk lə- /

noun

Pharmacology.

1. a synthetic, crystalline, toxic substance, C 7 H 15 Cl 2 N 2 O 2 P, related to nitrogen mustard, used in the treatment of Hodgkin's disease, lymphoma, and certain leukemias. CYC

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cyclophosphamide British  

/ ˌsaɪkləʊˈfɒsfəˌmaɪd /

noun

1. an alkylating agent used in the treatment of leukaemia and lymphomas

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Etymology

Origin of cyclophosphamide

First recorded in 1955–60; cyclo- + phosph- + amide

Example Sentences

From there, Eisman was diagnosed, underwent a double mastectomy and is being treated with two types of chemotherapy: Taxol and AC, or Adriamycin and cyclophosphamide.

From MarketWatch • Dec. 12, 2025

Nice said the drug cost £4,320 for a 1,800mg per 15ml vial and, along with bortezomib, cyclophosphamide and dexamethasone, was recommended as an option for treating newly diagnosed AL amyloidosis in adults.

From BBC • Mar. 4, 2024

A component of the chemotherapy, cyclophosphamide, also suppresses regulatory T cells, which inhibit killer T cell responses.

From Science Daily • Sep. 21, 2023

Brodsky reports that other teams are following his lead, and says the more gentle procedure using post-transplant cyclophosphamide is spreading across the United States and overseas.

From Nature • Nov. 11, 2014

It remains unclear whether the secret to Ildstad's recipe is the facilitating cells or the timing of a certain chemotherapy drug, called cyclophosphamide, that is used to prevent graft rejection and GvHD.

From Scientific American • Mar. 7, 2012