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cytotoxic

British

/ ˌsaɪtəʊtɒkˈsɪsɪtɪ, ˌsaɪtəʊˈtɒksɪk /

adjective

poisonous to living cells: denoting certain drugs used in the treatment of leukaemia and other cancers

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Other Word Forms

cytotoxicity noun

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The drug, daraxonrasib, showed improvements in survival and success compared with standard-of-care cytotoxic chemotherapy in patients with metastatic pancreatic ductal adenocarcinoma who had been previously treated.

From Barron's • Apr. 13, 2026

In 18 month old mice that received the mRNA treatment before vaccination, the number of cytotoxic T cells targeting ovalbumin doubled compared with untreated mice of the same age.

From Science Daily • Dec. 29, 2025

This subtype is cytotoxic, meaning it can destroy cells that enter or harm the body.

From Science Daily • Dec. 15, 2025

"These findings have important implications for cancer immunotherapy in general, as they identify a novel and eminently targetable checkpoint against the function of infiltrating cytotoxic T cells in the tumor microenvironment," said Coukos.

From Science Daily • Apr. 24, 2024

Checkpoint inhibitor therapies, for example, aim to release the blockade of fully differentiated cytotoxic T cells and "switch them back on."

From Science Daily • Apr. 24, 2024

Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023