degranulation
Americannoun
Etymology
Origin of degranulation
First recorded in 1940–45; de- + granulation
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
They eliminate these threats through a process called degranulation, which releases a protein known as perforin.
From Science Daily • Oct. 11, 2025
Additional experiments revealed that non-steroidal anti-inflammatory drugs suppressed the anti-allergic effects of SCFAs, and that vitamin B-3, which interacts with the GPR109A receptor, also inhibited MC degranulation.
From Science Daily • Feb. 1, 2024
This led to changes in the expression levels of the IgE-receptor, which ultimately inhibited degranulation in MCs.
From Science Daily • Feb. 1, 2024
IgE makes mast cell degranulation very specific, such that if a person is allergic to peanuts, there will be peanut-specific IgE bound to his or her mast cells.
From Textbooks • Jun. 19, 2013
As these mediators are released with mast cell degranulation, type I hypersensitivity reactions are usually rapid and occur within just a few minutes, hence the term immediate hypersensitivity.
From Textbooks • Jun. 19, 2013
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
