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Showing results for degranulation. Search instead for cell degranulation.

degranulation

American  
[dee-gran-yuh-ley-shuhn] / diˌgræn jəˈleɪ ʃən /

noun

  1. the loss or elimination of granules.


Etymology

Origin of degranulation

First recorded in 1940–45; de- + granulation

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

They eliminate these threats through a process called degranulation, which releases a protein known as perforin.

From Science Daily • Oct. 11, 2025

This led to changes in the expression levels of the IgE-receptor, which ultimately inhibited degranulation in MCs.

From Science Daily • Feb. 1, 2024

Additional experiments revealed that non-steroidal anti-inflammatory drugs suppressed the anti-allergic effects of SCFAs, and that vitamin B-3, which interacts with the GPR109A receptor, also inhibited MC degranulation.

From Science Daily • Feb. 1, 2024

Mast cell degranulation also occurs, and the fluid leakage caused by the increase in local vascular permeability is thought to have a flushing action on the parasite, expelling its larvae from the body.

From Textbooks • Jun. 19, 2013

IgE makes mast cell degranulation very specific, such that if a person is allergic to peanuts, there will be peanut-specific IgE bound to his or her mast cells.

From Textbooks • Jun. 19, 2013

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