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demyelinating disease

(dē-mīə-lə-nā′tĭng)
n.
  1. Any of a group of diseases of unknown cause in which there is extensive loss of the myelin sheaths of nerve fibers, as in multiple sclerosis.
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.