demyelination

[dee-mahy-uh-luh-ney-shuhn]

noun

1. loss of myelin from the nerve sheaths, as in multiple sclerosis.

Word History and Origins

Origin of demyelination¹

First recorded in 1930–35; de- + myelination

Example Sentences

After three weeks, mice that received cisplatin but not gamma therapy showed many of the expected effects of chemotherapy: brain volume shrinkage, DNA damage, demyelination, and inflammation.

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Moreover, behavioral deficits of the mice correlated more clearly with neurodegeneration than demyelination.

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The resulting demyelination impairs the functioning of nerve cells and can result in optic neuritis, vision loss, nausea and fatigue.

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Ziggy, estimated to be a teenager, suffers from cerebral demyelination that affects her coordination and ability to process images correctly.

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Unrelated work7 has shown that germ-free mice are protected from an experimentally induced condition similar to multiple sclerosis, which is characterized by demyelination of nerve fibres.

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