differentiation
Americannoun
-
the act or process of differentiating, or the state of being differentiated.
-
Mathematics. the operation of finding the differential or derivative of a function.
-
Biology. the process by which cells or tissues change from relatively generalized to specialized kinds, during development.
noun
-
the act, process, or result of differentiating
-
maths an operation used in calculus in which the derivative of a function or variable is determined; the inverse of integration See integration
-
any process in which a mixture of materials separates out partially or completely into its constituent parts, as in the cooling and solidification of a magma into two or more different rock types or in the gradual separation of an originally homogeneous earth into crust, mantle, and core
-
In calculus, the process of computing the derivative of a function.
-
Compare integration
-
The process by which cells or parts of an organism change during development to serve a specific function. The cells of an animal in its early embryonic phase, for example, are identical at first but develop by differentiation into specific tissues, such as bone, heart muscle, and skin. The factors determining the differentiation of any particular cell are not well understood, but in deuterostomes (vertebrates and other complex animals) they include the location of the cell relative to other cells.
Etymology
Origin of differentiation
First recorded in 1800–10; differentiat(e) + -ion
Explanation
Differentiation is how someone or something is set apart from others. If you make a differentiation between one brand of toothpaste and another, you point out how they're distinct. You can see the word different in differentiation. The -tion ending tips you off that differentiation is the noun form of different: differentiation refers to the differences themselves. Suppose two very similar movies come out at the same time. The studios will work to achieve differentiation in the films' trailers, with one highlighting the chemistry between the romantic leads and the other showing moments of slap-stick comedy.
Vocabulary lists containing differentiation
Cell Biology - Middle School
Looking to grow your vocabulary? Check out this interactive, curated word list from our team of English language specialists at Vocabulary.com – one of over 17,000 lists we've built to help learners worldwide!
Cell Biology - High School
Interested in learning more words like this one? Our team at Vocabulary.com has got you covered! You can review flashcards, quiz yourself, practice spelling, and more – and it's all completely free to use!
STAAR Biology: Cell Structure and Function
Want to remember this word for good? Start your learning journey today with our library of interactive, themed word lists built by the experts at Vocabulary.com – we'll help you make the most of your study time!
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
One challenge for the companies is differentiation, with multi-purpose vehicles emerging as a new battleground, with several new players targeting the 300,000 to 500,000 yuan range.
From The Wall Street Journal • Jun. 4, 2026
Students’ concerns prompted administrators to delay implementation until fall of 2027, not this fall as originally planned, so professors have time to redesign exams to allow for more differentiation.
From The Wall Street Journal • May 20, 2026
Traditionally, AI systems compute these derivatives using a process called recursive automatic differentiation.
From Science Daily • May 6, 2026
If competitive differentiation is the first thing investors look for when justifying such a high valuation, the second is a huge untapped market.
From Barron's • Apr. 30, 2026
They are generally speaking as mistrustful of wizards as they are of Muggles and indeed seem to make little differentiation between us.
From "Fantastic Beasts and Where to Find Them" by J.K. Rowling
![]()
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.