systemic lupus erythematosus

American  

noun

Pathology.

1. an autoimmune inflammatory disease of the connective tissues, occurring mainly among middle-aged women, chiefly characterized by skin eruptions, joint pain, recurrent pleurisy, and kidney disease. SLE

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systemic lupus erythematosus Scientific  

/ ĕr′ə-thē′mə-tō′sĭs /

1. An inflammatory autoimmune disease of the connective tissue, characterized by fever, skin rash, joint pain or arthritis, and anemia. It occurs most commonly in women and often affects the kidneys and nervous system, as well as other organs.

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Example Sentences

The drug, a treatment for the autoimmune disease systemic lupus erythematosus, is already approved as an intravenous infusion and that form of administration remains commercially available, AstraZeneca said.

From The Wall Street Journal • Feb. 3, 2026

The LiU researchers trained their autoencoder and then used the result to answer three different queries: age determination, smoker status and diagnosing the disease systemic lupus erythematosus, SLE.

From Science Daily • Oct. 11, 2023

As illustrated in Figure 33.28, systemic lupus erythematosus may affect the heart, joints, lungs, skin, kidneys, central nervous system, or other tissues, causing tissue damage via antibody binding, complement recruitment, lysis, and inflammation.

From Textbooks • Jun. 9, 2022

These include infections such as listeriosis; heart disorders such as cardiomyopathy; and autoimmune conditions such as flares of systemic lupus erythematosus.

From Nature • Mar. 23, 2020

The company asked the Food and Drug Administration to approve marketing of Benlysta for systemic lupus erythematosus, a disease in which the body's immune system attacks its own tissues and organs.

From Washington Post • Jun. 11, 2010