DNA repair

Cultural  

1. The way in which a cell corrects potentially damaging or mutagenic errors in its DNA. (See mutagen.) DNA bases may be directly replaced by enzymes, or part of a strand may be replaced by enzymes using its opposite, paired strand as a template.

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Example Sentences

In laboratory models, reducing the excessive DNA repair activity caused by abnormal TDP43 helped partially reverse cellular damage.

From Science Daily

"DNA repair is one of the most fundamental processes in biology," said lead investigator Muralidhar L. Hegde, Ph.D., professor of neurosurgery at the Houston Methodist Research Institute's Center for Neuroregeneration.

From Science Daily

"Many of these enzymes synthesize essential building blocks of life, and their nuclear localization is associated with DNA repair. Their presence in the nucleus may therefore directly shape how cancer cells respond to genotoxic stress, a hallmark of many chemotherapeutic treatments. It's an entirely new world to explore," says Dr. Sara Sdelci, corresponding author of the study and researcher at the Centre for Genomic Regulation.

From Science Daily

Some therapies target metabolic processes in cancer cells, while others focus on disrupting DNA repair systems.

From Science Daily

Using machine learning and other advanced analytical methods, the team identified a distinct pattern of gene activity related to DNA repair and stress response.

From Science Daily