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Down's syndrome

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noun Pathology.
  1. Down syndrome.
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Down syndrome

or Down's syndrome

noun Pathology.
  1. a genetic disorder, associated with the presence of an extra chromosome 21, characterized by mild to severe mental impairment, weak muscle tone, shorter stature, and a flattened facial profile.
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See also trisomy.

Origin of Down syndrome

1960–65; after John L. H. Down (1828–96), British physician
Also called trisomy 21.

Usage note

Down syndrome (or Down's syndrome ) has replaced earlier terms, such as mongolism to refer to the disease and Mongoloid or Mongol to refer to the affected person, all of which are now considered offensive.
Dictionary.com Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2018

British Dictionary definitions for down's syndrome

Down's syndrome

US Down syndrome

noun
    1. pathola condition caused by the presence of an extra copy of chromosome 21 resulting in learning difficulties and physical differences, such as shorter statureFormer name: offensive mongolism Technical name: trisomy 21
    2. (as modifier)a Down's syndrome baby
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Word Origin

C19: after John Langdon-Down (1828–96), English physician

usage

Although the condition was once generally known as mongolism, this term has been considered offensive since the early 1960s. The terms Down's syndrome or (US) Down syndrom are now preferred.
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Word Origin and History for down's syndrome

Down's Syndrome

1961, from J.L.H. Down (1828-1896), English physician; chosen as a less racist name for the condition than earlier mongolism.

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Online Etymology Dictionary, © 2010 Douglas Harper

down's syndrome in Medicine

Down syndrome

(doun)
n.
  1. A congenital disorder, caused by the presence of an extra 21st chromosome, in which the affected person has mild to moderate mental retardation, short stature, and a flattened facial profile.trisomy 21 trisomy 21 syndrome
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The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.

down's syndrome in Science

Down syndrome

[doun]
  1. A congenital disorder caused by the presence of an extra 21st chromosome. People with Down syndrome have mild to moderate mental retardation, short stature, and a flattened facial profile. The syndrome is named after its discoverer, British physician John Langdon Haydon Down (1828-1896).
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The American Heritage® Science Dictionary Copyright © 2011. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

down's syndrome in Culture

Down's syndrome

A congenital condition, caused by an abnormality in the chromosomes, marked by moderate to severe mental retardation and changes in certain physical features.

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The New Dictionary of Cultural Literacy, Third Edition Copyright © 2005 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.