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encephalopathy

American  
[en-sef-uh-lop-uh-thee] / ɛnˌsɛf əˈlɒp ə θi /

noun

Psychiatry.
  1. any brain disease.


encephalopathy British  
/ ɛnˌsɛfəˈlɒpəθɪ /

noun

  1. any degenerative disease of the brain, often associated with toxic conditions See also BSE

"Collins English Dictionary — Complete & Unabridged" 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

encephalopathy Scientific  
/ ĕn-sĕf′ə-lŏpə-thē /
  1. Degeneration of brain function, caused by any of various acquired disorders, including metabolic disease, organ failure, inflammation, and chronic infection.


Etymology

Origin of encephalopathy

First recorded in 1865–70; encephalo- + -pathy

Vocabulary lists containing encephalopathy

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

Disruptions have been linked to metabolic and neurological conditions such as liver failure and encephalopathy, as well as aging-related disorders like Alzheimer's and Parkinson's disease.

From Science Daily Apr. 13, 2026

And as a bonus, there is virtually zero risk of the repeated helmet-to-helmet hitting linked to chronic traumatic encephalopathy and early-onset dementia.

From Los Angeles Times Mar. 13, 2026

That table, for instance, lists certain forms of encephalopathy — a type of brain dysfunction — as a rare side effect of shots that protect people from whooping cough, measles, mumps and rubella.

From Salon Jul. 17, 2025

Repeated head blows can cause something called chronic traumatic encephalopathy, or CTE, which gets worse over time and can lead to dementia.

From BBC Sep. 18, 2024

Mr. Zucker had suffered numerous health problems since being injured in a car crash in 2022, including, near the end of his life, metabolic encephalopathy and three underlying infections.

From New York Times May 23, 2024

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