endogenous depression

American  

noun

Psychiatry.

1. a severe form of depression usually characterized by insomnia, weight loss, and inability to experience pleasure, thought to be of internal origin and not influenced by external events.

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Etymology

Origin of endogenous depression

First recorded in 1960–65

Example Sentences

At two I began a lifetime of chronic asthma, full blown obsessive compulsive disorder starting around puberty, years of scrupulous hyper-religiosity and hints of endogenous depression.

From Scientific American • Jun. 29, 2012

The wisdom of the time was that endogenous depression affected, at the most, about 1 in 1,000 people at some time in their lives.

From Time Magazine Archive