endosome

American  

[en-duh-sohm] / ˈɛn dəˌsoʊm /

noun

Cell Biology.

1. a smooth sac within the cell, formed by or fused with coated vesicles that shed their clathrin, in which ligands are separated from their receptors and from which the receptors are returned to the cell surface.

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Etymology

Origin of endosome

endo- + -some ³

Example Sentences

"We spent a lot of time figuring out how these non-coding RNAs get to the endosome, since that's not where they usually reside," He explained.

From Science Daily • Nov. 30, 2025

When accessible nutrients from the degradation of the vesicular contents have been extracted, the newly formed endosome merges with the plasma membrane and releases its contents into the extracellular fluid.

From Textbooks • Jun. 9, 2022

The shape of ionizable lipids affects an LNP’s ability to disrupt an endosome, as does cholesterol, one of the other fats in LNPs.

From Science Magazine • May 12, 2022

Then it is engulfed in a hollow bubble called an endosome.

From Scientific American • Feb. 11, 2022

Alternatively, the effect of LRRK2 mutations on the accumulation of α-synuclein might be indirect, the result of more general endosome and lysosome dysfunction.

From Nature • Nov. 8, 2016