"an epidemic disease," especially the plague, late 15c., ipedemye, impedyme, from Old French ypidime (12c., Modern French épidémie), from Late Latin epidemia (see epidemic (adj.)).
Examples from the Web for epidemy
I have no doubt but the epidemy, which has been ravaging Spain lately, is the same disorder with the one above described.
Alas, for the epidemy to which, few can doubt, ideas are subject!The Complete Prose Works of Martin Farquhar Tupper|Martin Farquhar Tupper
All the relatives of L'Hage Abdallah have fallen victims to the epidemy.
Signor Conton died this morning of the epidemy; yesterday afternoon he was apparently quite well, and paid me a visit.
He distinguishes carefully pestilence from epidemy and endemy.The Black Death, and The Dancing Mania|Justus Friedrich Karl Hecker