erk
Americannoun
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an aircraftsman of the lowest rank in the Royal Air Force.
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a worthless, stupid person; jerk.
noun
Etymology
Origin of erk
First recorded in 1920–25; earlier naval slang for any noncommissioned rank; of uncertain origin
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
Indeed, a core finding of the Science papers was that activation of the ERK protein alone is the key driver of resistance to drugs that inhibit KRAS.
From Science Daily • Jun. 6, 2024
When the team combined DRP-104 with an existing drug that blocks the ERK signaling pathway, trametinib, it further improved survival in pancreatic cancer mouse models compared to DRP-104 treatment alone.
From Science Daily • Oct. 9, 2023
An example of a protein that regulates translation in the nucleus is the MAP kinase ERK.
From Textbooks • Jun. 9, 2022
ERK phosphorylates MNK1, which in turn phosphorylates eIF-4E, an elongation initiation factor that, with other initiation factors, is associated with mRNA.
From Textbooks • Jun. 9, 2022
Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors.
From Nature • Apr. 22, 2018
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
