estradiol
Americannoun
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Biochemistry. an estrogenic hormone, C 18 H 24 O 2 , produced by the maturing Graafian follicle, that causes proliferation and thickening of the tissues and blood vessels of the endometrium.
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Pharmacology. a commercial form of this compound, obtained from the urine of pregnant humans and mares or synthesized, used in the treatment of estrogen deficiency and certain menopausal and postmenopausal conditions.
noun
Etymology
Origin of estradiol
1930–35; estra- (combining form representing estrin ) + di- 1 + -ol 1
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
Treatment with estradiol, a form of estrogen, reversed the reduction in stem cell proliferation.
From Science Daily ● Oct. 18, 2026
There are surprisingly few contraindications to oral estradiol, and women can talk to their doctors to see if this is an option.
From MarketWatch ● May 12, 2026
Demand is up for several reasons; more doctors are prescribing the transdermal bioidentical estradiol, and the manufacturing process for patches is more labor-intensive and time-consuming than making pills.
From MarketWatch ● May 12, 2026
“I’d rather do without bread than my estradiol patch,” Polo said.
From The Wall Street Journal ● Feb. 7, 2026
Felicia Zigman, 54, who has been using estradiol patches for about nine months, said that a pharmacist told her to talk to her doctor about increasing her dosage, given the shortage of starting-dosage patches.
From The Wall Street Journal ● Feb. 7, 2026
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