[ es-truh-dahy-awl, -ol ]
/ ˌɛs trəˈdaɪ ɔl, -ɒl /


Biochemistry. an estrogenic hormone, C18H24O2, produced by the maturing Graafian follicle, that causes proliferation and thickening of the tissues and blood vessels of the endometrium.
Pharmacology. a commercial form of this compound, obtained from the urine of pregnant humans and mares or synthesized, used in the treatment of estrogen deficiency and certain menopausal and postmenopausal conditions.

Origin of estradiol

1930–35; estra- (combining form representing estrin) + di-1 + -ol1 Unabridged Based on the Random House Unabridged Dictionary, © Random House, Inc. 2020

British Dictionary definitions for estradiol

/ (ˌɛstrəˈdaɪɒl, ˌiːstrə-) /


the US spelling of oestradiol
Collins English Dictionary - Complete & Unabridged 2012 Digital Edition © William Collins Sons & Co. Ltd. 1979, 1986 © HarperCollins Publishers 1998, 2000, 2003, 2005, 2006, 2007, 2009, 2012

Medical definitions for estradiol

[ ĕs′trə-dīôl′, -ōl′ ]


The most potent naturally occurring estrogen.
The American Heritage® Stedman's Medical Dictionary Copyright © 2002, 2001, 1995 by Houghton Mifflin Company. Published by Houghton Mifflin Company.