estradiol
Americannoun
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Biochemistry. an estrogenic hormone, C 18 H 24 O 2 , produced by the maturing Graafian follicle, that causes proliferation and thickening of the tissues and blood vessels of the endometrium.
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Pharmacology. a commercial form of this compound, obtained from the urine of pregnant humans and mares or synthesized, used in the treatment of estrogen deficiency and certain menopausal and postmenopausal conditions.
noun
Etymology
Origin of estradiol
1930–35; estra- (combining form representing estrin ) + di- 1 + -ol 1
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
Bioidentical estradiol, which is the most common form used today, was not included in the WHI.
From MarketWatch ● May 12, 2026
Let’s not forget oral estradiol: Bioidentical estradiol tablets are considered both safe and effective for most women.
From MarketWatch ● May 12, 2026
Felicia Zigman, 54, who has been using estradiol patches for about nine months, said that a pharmacist told her to talk to her doctor about increasing her dosage, given the shortage of starting-dosage patches.
From The Wall Street Journal ● Feb. 7, 2026
More than 142 million units of estradiol patches were sold in 2025, according to data from IQVIA, up from about 46.5 million units five years earlier.
From The Wall Street Journal ● Feb. 7, 2026
A new study led by Johns Hopkins Medicine takes a closer look at whether sex hormones, including testosterone and estradiol, may help explain why these risks vary.
From Science Daily ● Feb. 4, 2026
Definitions and idiom definitions from Dictionary.com Unabridged, based on the Random House Unabridged Dictionary, © Random House, Inc. 2023
Idioms from The American Heritage® Idioms Dictionary copyright © 2002, 2001, 1995 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company.
